Dr. Eric Parrish is the Chief of the Psychiatric Unit at Havemeyer General Hospital outside of Philadelphia. Recently separated from his wife Alice, he is doing his best as a single Dad to his seven-year-old daughter Hannah. Taking on a new patient, Eric's entire world begins to crumble. Seventeen-year-old Max has a terminally ill grandmother and is having trouble handling it. That, plus his OCD and violent thoughts about a girl he likes makes Eric a high risk patient. When the girl is found murdered, Max is nowhere to be found. Worried about Max, Eric goes looking for him and puts himself in danger of being seen as a "person of interest" himself.